The Handmaid's Tale
Set in the future, this book's protagonist is a handmaid (concubine) who recounts her life in a restrictive society, and it's also full of sex, drama and secret underground clubs that are intent on overthrowing the government.
Wilderness Tips (short stories)
One of the stories in this collection, "Death by Landscape," is a story about a woman who is reminiscing about some real crappy stuff that happened to her in the woods, but, surprise, it's totally a deep look at life and the way people cope with tragedies.
Oryx and Crake
Oryx and Crake also takes place in the future and it's a novel filled with hybrid pig animals, factory-made chicken, a semi-creepy manufactured breed of humans, and, oh yeah, civilization has collapsed.